St. Anthony lies on the west slope of the Continental Divide on the banks of the world famous fly-fishing River the Henry's Fork of the Snake River. Agriculture is the main industry here with an emphasis on potatoes, grain and cattle. However several other industries such as lumber, dairy and related businesses can also be found here. St. Anthony is also becoming a technological hub, with a major Information Technology firm having it's International offices here.

With 10,600 acres of white quartz sand blown into 400 foot high dunes, this is the ultimate playground for off-road vehicle enthusiasts. Today the St. Anthony Sand Dunes are home to a Wilderness Study Area and one of the largest herds of wintering elk in the United States.